Sleep-Disordered Breathing in a Group of Heart Transplantation Candidates
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Abstract
Background and Objective: Sleep-Disordered Breathing (SDB) is associated with increased morbidity and mortality in patients with heart failure (HF). We assessed the prevalence and the pattern of SDB in HF patients who were candidates for heart transplantation.
Materials and Methods: Twenty heart transplantation patients with ventricular ejection-fraction < 25% were recruited consecutively in a cross-sectional study in Iran during 2009-2010. Full-night polysomnography was performed for them.
Results: The participants consisted of 14 males and 6 females with the mean ± SD age of 45.6 ±13.3 and the mean ± SD Body Mass Index (BMI) of 24.1±5.5. Seventeen patients (85%) were diagnosed with sleep breathing disorder, among which, four had central sleep apnea.
Conclusions: Sleep apnea is prevalent in heart transplantation candidates.
Wolk R, Kara T, Somers VK. Sleep-disordered breathing and cardiovascular disease. Circulation 2003;108:9-12.
Ferrier K, Campbell A, Yee B, et al. SLeep- disordered breathing occurs frequently in stable out- patients with congestive heart failure. Chest 2005;128:2116-22.
Schulz R, Blau A, Börgel J, et al. Sleep apnoea in heart failure. Eur Respir J 2007;29:1201-5.
Oldenburg O, Lamp B, Faber L, Teschler H, Horstkotte D, Töpfer V. Sleep-disordered breathing in patients with symptomatic heart failure A contem-porary study of prevalence in and characteristics of 700 patients. Eur J Heart Fail 2007;9:251-7.
Garrigue S, Bordier P, Jais P, et al. Benefit of atrial pacing in sleep apnea syndrome. N Engl J Med 2002;346:404-12.
Walsh JT, Andrews R, Starling R, Cowley AJ, Johnston ID, Kinnear WJ. Effects of captopril and oxygen on sleep apnoea in patients with mild to moderate congestive cardiac failure. Br Heart J 1995;73:237-41.
Lanfranchi PA, Somers VK, Braghiroli A, Cor- ra U, Eleuteri E, Giannuzzi P. Central sleep apnea in left ventricular dysfunction: prevalence and implica-tions for arrhythmic risk. Circulation 2003;107:727-32.
Andreas S, Hagenah G, Moller C, Werner GS, Kreuzer H. Cheyne-Stokes respiration and prognosis in congestive heart failure. Am J Cardiol 1996;78:1260-4.
Hanly PJ, Zuberi-Khokhar NS. Increased mor- tality associated with Cheyne-Stokes respiration in patients with congestive heart failure. Am J Respir Crit Care Med 1996;153:272-6.
Vazir A, Hastings PC, Dayer M, et al. A high prevalence of sleep disordered breathing in men with mild symptomatic chronic heart failure due to left ventricular systolic dysfunction. Eur J Heart Fail 2007;9:243-50.
Sin DD, Fitzgerald F, Parker JD, Newton G, Floras JS, Bradley TD. Risk factors for central and obstructive sleep apnea in 450 men And women with congestive heart failure. Am J Respir Crit Care Med 1999;160:1101-6.
Shahar E, Whitney CW, Redline S, et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the sleep heart health study. Am J Respir Crit Care Med 2001;163:19-25.
Kazimierczak A, Krzesinski P, Krzyzanowski K, Gielerak G. Sleep-disordered breathing in patients with heart failure: new trends in therapy. Biomed ResInt 2013;2013:459613.
Sin DD, Man GC. Cheyne-Stokes respiration:a consequence of a broken heart? Chest 2003;124:1627-8.
| Files | ||
| Issue | Vol 1 No 1 (2016): Winter | |
| Section | Original Article(s) | |
| Keywords | ||
| Heart failure Heart transplantation Obstructive sleep apnea Central sleep apnea | ||
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