Tehran University of Medical Sciences Journal of Sleep Sciences 2476-2938 1 1 2015 11 08 13 17 EN Mojahede Salmani Nodoushan Department of Occupational Medicine, Medical School, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Industrial Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Farzaneh Chavoshi Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran 2015 11 08 2015 11 08 Background and Objective: Depression is commonly reported in patients with Obstructive Sleep Ap- nea/Hypopnea Syndrome (OSAS). We aimed to assess the association between OSAS severity and depressive symptoms in patients with OSAS. Materials and Methods: A total of 337 patients with symptoms of OSAS were visited for psychological testing prior to beginning diagnosis for the syndrome between 2012 -2014 in Baharloo Hospital. Participants completed the Beck Depression Inventory-II (BDI-II) and Epworth Sleepiness Scale (ESS) questionnaires. Res- piratory Disturbance Index (RDI), mean of arterial oxygen saturation, sleep efficiency, and number of awaken- ings were measured by polysomnography (PSG). Results: Correlation between RDI index and ESS score was statistically significant (r: 0.215, P<0.001), but correlation between RDI and BDI-II score was not statistically significant (P= 0.59). Also mean of BDI-II score between male and female was statistically different (male: 12.08 ± 10.6, female: 17.26 ± 12.56, P<0.001). Conclusions: OSAS severity was not related to symptoms of depression measured by BDI-II questionnaire.It seems that the method of scoring for depression severity may affect the association between obstructive sleep apnea and depression. https://jss.tums.ac.ir/index.php/jss/article/view/8 https://jss.tums.ac.ir/index.php/jss/article/download/8/4