Tehran University of Medical Sciences Journal of Sleep Sciences 2476-2938 1 2 2016 07 27 74 79 EN Zahra Banafsheh Alemohammad Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical sciences, Tehran, Iran Seyed Mohammad Esmaeil Taghavi Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical sciences, Tehran, Iran Akbar Sharifian Occupational Medicine Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2015 11 14 2016 02 29 Background and Objective: Restless legs syndrome (RLS) is a sleep disorder with an association to sleep quality. We investigated the sleep quality in patients with RLS among health-care workers with or without shift work. Materials and Methods: All female health-care workers (n = 540) in four educational hospitals were enrolled in this cross-sectional study. International RLS Study Group (IRLSSG) questionnaire, IRLSSG Rating Scale, Pittsburgh Sleep Quality Index (PSQI), and a data collection sheet including demographic characteristics and disorders related to secondary RLS were completed by study participants. Results: The mean ± standard deviation (SD) age of the participants was 32.0 ± 6.8 years. The mean ± SD PSQI scores were 9.03 ± 3.29 and 7.30 ± 3.67 in RLS-positive and RLS-negative shift workers (P = 0.002), respectively. The mean ± SD PSQI scores were 7.76 ± 3.66 and 6.10 ± 3.15 in RLS-positive and RLS-negative non-shift workers (P = 0.005), respectively. Conclusion: Health-care workers have poor sleep quality aggravated with both RLS and shift work. RLS-positive female patients are at increased risk of poor sleep quality in both shift workers and non-shift workers with the worst score of PSQI questionnaire in shift workers. https://jss.tums.ac.ir/index.php/jss/article/view/14 https://jss.tums.ac.ir/index.php/jss/article/download/14/28