Tehran University of Medical Sciences Journal of Sleep Sciences 2476-2938 1 1 2015 11 08 28 33 EN Abolfazl Mozafari Department of Medical Sciences, Qom Branch, Islamic Azad University, Qom, Iran Seied Fakhredin Hejazi Department of Medical Sciences, Qom University of Medical Sciences, Qom, Iran Zahra Afrakhteh Department of Medical Sciences, Qom University of Medical Sciences, Qom, Iran Fazeleh Shakeri Department of Medical Sciences, Qom University of Medical Sciences, Qom, Iran Siamak Mohebi Department of Public Health, School of Health, Qom University of Medical Sciences, Qom, Iran Hadi Zamanian Department of Public Health, School of Health, Tehran University of Medical Sciences, Tehran, Iran 2015 11 08 2015 11 08 Background and Objective: Obstructive sleep apnea (OSA) is frequent and in some degree it affects about 24% of male and 9% of female in middle age adults. This study aimed to assess the association between risk of OSA and CAD. Materials and Methods: This case-control study was performed among 184 patients with a history of coro- nary angiography in two catheter labs at hospitals in Qom, Iran. Control group had normal or minimal coronary stenosis (<50%) and case group had 1, 2 or 3 coronary vessel disease. All the patients completed demographic and Berlin questionnaires and then data were analyzed using SPSS version 16. Results: Mean (±SD) age of participants was 55.36 ± 10 years. A total of 119 (61.4%) patients were female. This study showed significant difference between risk of OSA in patients with CAD and those without CAD (OR=1.25), hypertension (OR=10.4) and non-insulin dependent diabetes mellitus (OR=2.12), but there were no correlation between risk of OSA and ejection fraction less than 45% (P value=0.582). Conclusions: OSA can be considered as one of the important risk factors for CAD. https://jss.tums.ac.ir/index.php/jss/article/view/11 https://jss.tums.ac.ir/index.php/jss/article/download/11/7